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TitleMolecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 111, Page 6275-6280, Year 2014
Publish dateFeb 4, 2014 (structure data deposition date)
AuthorsDunkle, J.A. / Vinal, K. / Desai, P.M. / Zelinskaya, N. / Savic, M. / West, D.M. / Conn, G.L. / Dunham, C.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:24717845
MethodsX-ray diffraction
Resolution3.8035 Å
Structure data

PDB-4ox9:
Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit
Method: X-RAY DIFFRACTION / Resolution: 3.8035 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-SFG:
SINEFUNGIN

Source
  • escherichia coli (E. coli)
  • thermus thermophilus (bacteria)
KeywordsRIBOSOME/ANTIBIOTIC / Protein biosynthesis / ribosome / RNA / 30S / 16S / ribosomal subunit / aminoglycoside / A1408 / methyltransferase / RIBOSOME-ANTIBIOTIC complex

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