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TitleDiscovery and the structural basis of a novel p21-activated kinase 4 inhibitor.
Journal, issue, pagesCancer Lett., Vol. 349, Page 45-50, Year 2014
Publish dateNov 9, 2013 (structure data deposition date)
AuthorsRyu, B.J. / Kim, S. / Min, B. / Kim, K.Y. / Lee, J.S. / Park, W.J. / Lee, H. / Kim, S.H. / Park, S.
External linksCancer Lett. / PubMed:24704155
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-4njd:
Structure of p21-activated kinase 4 with a novel inhibitor KY-04031
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-NJD:
N-(1H-indazol-5-yl)-N'-[2-(1H-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTransferase/Transferase inhibitor / Kinase / Transferase-Transferase inhibitor complex

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