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Structure paper

TitleStructural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor beta / delta (FABP5-PPAR beta / delta ) signaling pathway.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 14941-14954, Year 2014
Publish dateJul 8, 2013 (structure data deposition date)
AuthorsArmstrong, E.H. / Goswami, D. / Griffin, P.R. / Noy, N. / Ortlund, E.A.
External linksJ. Biol. Chem. / PubMed:24692551
MethodsX-ray diffraction
Resolution1.67 - 2.57 Å
Structure data

PDB-4lkp:
Crystal Structure of Apo Human Epidermal Fatty Acid Binding Protein (FABP5)
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

PDB-4lkt:
Crystal Structure of Human Epidermal Fatty Acid Binding Protein (FABP5) in Complex with Linoleic Acid
Method: X-RAY DIFFRACTION / Resolution: 2.57 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-NH4:
AMMONIUM ION

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-EIC:
LINOLEIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-TAR:
D(-)-TARTARIC ACID

ChemComp-CIT:
CITRIC ACID

Source
  • homo sapiens (human)
KeywordsLIPID BINDING PROTEIN / Beta Barrel / Beta Clam / Fatty Acid Binding Protein / Fatty Acids / Nucleus

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