+Search query
-Structure paper
Title | Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 24, Page 2206-2211, Year 2014 |
Publish date | Dec 6, 2013 (structure data deposition date) |
![]() | Shi, Q. / Tebben, A. / Dyckman, A.J. / Li, H. / Liu, C. / Lin, J. / Spergel, S. / Burke, J.R. / McIntyre, K.W. / Olini, G.C. ...Shi, Q. / Tebben, A. / Dyckman, A.J. / Li, H. / Liu, C. / Lin, J. / Spergel, S. / Burke, J.R. / McIntyre, K.W. / Olini, G.C. / Strnad, J. / Surti, N. / Muckelbauer, J.K. / Chang, C. / An, Y. / Cheng, L. / Ruan, Q. / Leftheris, K. / Carter, P.H. / Tino, J. / De Lucca, G.V. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.03 Å |
Structure data | ![]() PDB-4nwm: |
Chemicals | ![]() ChemComp-2P5: ![]() ChemComp-HOH: |
Source |
|
![]() | TRANSFERASE/TRANSFERASE INHIBITOR / KINASE / BTK / ATK / XLA / PSCTK1 / AGMX1 / AT / IMD1 / MGC126261 / MGC126262 BPK / TRANSFERASE-TRANSFERASE INHIBITOR complex |