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TitleThe 2.1 A Resolution Structure of Cyanopindolol-Bound Beta1- Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor.
Journal, issue, pagesPlos One, Vol. 9, Page 92727-, Year 2014
Publish dateJun 26, 2013 (structure data deposition date)
AuthorsMiller-Gallacher, J.L. / Nehme, R. / Warne, T. / Edwards, P.C. / Schertler, G.F.X. / Leslie, A.G.W. / Tate, C.G.
External linksPlos One / PubMed:24663151
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-4bvn:
Ultra-thermostable beta1-adrenoceptor with cyanopindolol bound
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-P32:
4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile

ChemComp-MHA:
(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID / pH buffer*YM

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-HOH:
WATER

Source
  • meleagris gallopavo (turkey)
KeywordsSIGNALING PROTEIN

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