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TitleThe structure and substrate specificity of human Cdk12/Cyclin K.
Journal, issue, pagesNat Commun, Vol. 5, Page 3505-3505, Year 2014
Publish dateNov 29, 2013 (structure data deposition date)
AuthorsBosken, C.A. / Farnung, L. / Hintermair, C. / Merzel Schachter, M. / Vogel-Bachmayr, K. / Blazek, D. / Anand, K. / Fisher, R.P. / Eick, D. / Geyer, M.
External linksNat Commun / PubMed:24662513
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-4nst:
Crystal structure of human Cdk12/Cyclin K in complex with ADP-aluminum fluoride
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-AF3:
ALUMINUM FLUORIDE

ChemComp-MG:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSCRIPTION / transcription / RNA polymerase II / phosphorylation / TRANSFERASE-TRANSCRIPTION complex

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