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TitleUnderstanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.
Journal, issue, pagesFebs J., Vol. 281, Page 4224-4239, Year 2014
Publish dateOct 24, 2012 (structure data deposition date)
AuthorsWang, F. / Singh, S. / Zhang, J. / Huber, T.D. / Helmich, K.E. / Sunkara, M. / Hurley, K.A. / Goff, R.D. / Bingman, C.A. / Morris, A.J. ...Wang, F. / Singh, S. / Zhang, J. / Huber, T.D. / Helmich, K.E. / Sunkara, M. / Hurley, K.A. / Goff, R.D. / Bingman, C.A. / Morris, A.J. / Thorson, J.S. / Phillips, G.N.
External linksFebs J. / PubMed:24649856
MethodsX-ray diffraction
Resolution2.189 - 2.494 Å
Structure data

PDB-4hpv:
Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus
Method: X-RAY DIFFRACTION / Resolution: 2.214 Å

PDB-4k0b:
Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus complexed with SAM and PPi
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

PDB-4l2z:
Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus complexed with SAE and PPi
Method: X-RAY DIFFRACTION / Resolution: 2.494 Å

PDB-4l7i:
Crystal structure of S-Adenosylmethionine synthase from Sulfolobus solfataricus complexed with SAM and PPi
Method: X-RAY DIFFRACTION / Resolution: 2.189 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-DPO:
DIPHOSPHATE

ChemComp-PO4:
PHOSPHATE ION

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-S7M:
[(3S)-3-amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}ethyls

Source
  • sulfolobus solfataricus (archaea)
KeywordsTRANSFERASE / Structural Genomics / PSI-Biology / Protein Structure Initiative / Enzyme Discovery for Natural Product Biosynthesis / NatPro / S-adenosylmethionine synthase

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