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Structure paper

TitleStructural basis of the proinflammatory signaling complex mediated by TSLP.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 21, Page 375-382, Year 2014
Publish dateNov 16, 2013 (structure data deposition date)
AuthorsVerstraete, K. / van Schie, L. / Vyncke, L. / Bloch, Y. / Tavernier, J. / Pauwels, E. / Peelman, F. / Savvides, S.N.
External linksNat. Struct. Mol. Biol. / PubMed:24632570
MethodsX-ray diffraction
Resolution1.898 - 3.775 Å
Structure data

PDB-4nn5:
Cytokine receptor complex - Crystal form 1A
Method: X-RAY DIFFRACTION / Resolution: 1.898 Å

PDB-4nn6:
Cytokine receptor complex - Crystal form 1B
Method: X-RAY DIFFRACTION / Resolution: 2.545 Å

PDB-4nn7:
Cytokine receptor complex - Crystal form 2
Method: X-RAY DIFFRACTION / Resolution: 3.775 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsCYTOKINE/CYTOKINE RECEPTOR / four helical bundle fold / CHR domains / TSLP cytokine signaling / TSLPR and IL-7Ralpha receptors / cell surface / CYTOKINE-CYTOKINE RECEPTOR complex

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