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-Structure paper
Title | Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis. |
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Journal, issue, pages | Chembiochem, Vol. 15, Page 852-864, Year 2014 |
Publish date | Aug 9, 2012 (structure data deposition date) |
![]() | Evans, G.L. / Gamage, S.A. / Bulloch, E.M. / Baker, E.N. / Denny, W.A. / Lott, J.S. |
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Methods | X-ray diffraction |
Resolution | 1.667 - 1.96 Å |
Structure data | ![]() PDB-4giu: ![]() PDB-4gkm: ![]() PDB-4ij1: ![]() PDB-4m0r: |
Chemicals | ![]() ChemComp-PRP: ![]() ChemComp-MG: ![]() ChemComp-636: ![]() ChemComp-GOL: ![]() ChemComp-DMS: ![]() ChemComp-HOH: ![]() ChemComp-683: ![]() ChemComp-17C: ![]() ChemComp-IMD: ![]() ChemComp-644: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / Magnesium binding / phophoribosylpyrophosphate / PRPP / inhibitor complex / bi-anthranilate-like analogue / TB Structural Genomics Consortium / TBSGC / phosphoribosyltransferase / TRANSFERASE-TRANSFERASE INHIBITOR complex / phosphoribosylpyrophosphate / bi-anthranilate analogue / tri-anthranilate analogue / transferase |