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Structure paper

TitleHow a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 136, Page 4927-4937, Year 2014
Publish dateJan 3, 2013 (structure data deposition date)
AuthorsWu, W.J. / Su, M.I. / Wu, J.L. / Kumar, S. / Lim, L.H. / Wang, C.W. / Nelissen, F.H. / Chen, M.C. / Doreleijers, J.F. / Wijmenga, S.S. / Tsai, M.D.
External linksJ. Am. Chem. Soc. / PubMed:24617852
MethodsNMR (solution)
Structure data

PDB-2m2t:
ASFV Pol X structure
Method: SOLUTION NMR

PDB-2m2u:
Binary complex of African Swine Fever Virus Pol X with MgdGTP
Method: SOLUTION NMR

PDB-2m2v:
African Swine Fever Virus Pol X in the ternary complex with MgdGTP and DNA
Method: SOLUTION NMR

PDB-2m2w:
Ternary complex of ASFV Pol X with DNA and MgdGTP
Method: SOLUTION NMR

Chemicals

ChemComp-DGT:
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

Source
  • african swine fever virus
KeywordsTRANSFERASE / DNA polymerase / Nucleotidyl Transferase / TRANSFERASE/DNA / ASFV Pol X / TRANSFERASE-DNA complex

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