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TitleCrystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-beta
Journal, issue, pagesACTA CRYSTALLOGR. ,SECT. F, Vol. 70, Page 374-377, Year 2014
Publish dateJan 21, 2014 (structure data deposition date)
AuthorsCrespi, G.A.N. / Ascher, D.B. / Parker, M.W. / Miles, L.A.
External linksACTA CRYSTALLOGR. ,SECT. F / PubMed:24598931
MethodsX-ray diffraction
Resolution1.998 Å
Structure data

PDB-4ojf:
Humanised 3D6 Fab complexed to amyloid beta 1-8
Method: X-RAY DIFFRACTION / Resolution: 1.998 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / amyloid / bapineuzumab / 3D6 / alzheimer's disease / immunoglobulin / immunotherapy / amyloid beta

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