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TitleMolecular functions of the TLE tetramerization domain in Wnt target gene repression.
Journal, issue, pagesEmbo J., Vol. 33, Page 719-731, Year 2014
Publish dateJan 25, 2014 (structure data deposition date)
AuthorsChodaparambil, J.V. / Pate, K.T. / Hepler, M.R. / Tsai, B.P. / Muthurajan, U.M. / Luger, K. / Waterman, M.L. / Weis, W.I.
External linksEmbo J. / PubMed:24596249
MethodsX-ray diffraction
Resolution2.855 - 4 Å
Structure data

PDB-4om2:
Crystal structure of TLE1 N-terminal Q-domain residues 1-156
Method: X-RAY DIFFRACTION / Resolution: 4 Å

PDB-4om3:
Crystal structure of human TLE1 Q-domain residues 20-156
Method: X-RAY DIFFRACTION / Resolution: 2.855 Å

Chemicals

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsTranscription / DNA binding / tetramer / helix-turn-helix / Wnt repressor / TCF/LEF

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