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-Structure paper
Title | Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 111, Page 4227-4232, Year 2014 |
Publish date | Jun 4, 2013 (structure data deposition date) |
Authors | Stsiapanava, A. / Olsson, U. / Wan, M. / Kleinschmidt, T. / Rutishauser, D. / Zubarev, R.A. / Samuelsson, B. / Rinaldo-Matthis, A. / Haeggstrom, J.Z. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:24591641 |
Methods | X-ray diffraction |
Resolution | 1.618 - 1.72 Å |
Structure data | PDB-4l2l: PDB-4mkt: PDB-4ms6: |
Chemicals | ChemComp-ZN: ChemComp-1V6: ChemComp-YB: ChemComp-ACT: ChemComp-HOH: ChemComp-28T: ChemComp-ACY: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / Metalloprotein / Hydrolase / protease / Zinc binding / HYDROLASE-HYDROLASE INHIBITOR complex / Leukotriene A4 Hydrolase |