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Structure paper

TitleStructural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1.
Journal, issue, pagesStructure, Vol. 22, Page 612-, Year 2014
Publish dateJan 21, 2014 (structure data deposition date)
AuthorsZhao, Y. / Malinauskas, T. / Harlos, K. / Jones, E.Y.
External linksStructure / PubMed:24582434
MethodsX-ray diffraction
Resolution1.75 - 1.77 Å
Structure data

PDB-4cnc:
Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

PDB-4cnm:
Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CIT:
CITRIC ACID

Source
  • homo sapiens (human)
KeywordsCELL ADHESION / WAIF1 / TPBG / TROVAX / CANCER / SIGNALING / LEUCINE-RICH REPEATS / WNT/BETA-CATENIN SIGNALING PATHWAY / MVA-5T4

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