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Structure paper

TitleComputational design of the affinity and specificity of a therapeutic T cell receptor.
Journal, issue, pagesPLOS COMPUT. BIOL., Vol. 10, Page e1003478-e1003478, Year 2014
Publish dateJun 5, 2013 (structure data deposition date)
AuthorsPierce, B.G. / Hellman, L.M. / Hossain, M. / Singh, N.K. / Vander Kooi, C.W. / Weng, Z. / Baker, B.M.
External linksPLOS COMPUT. BIOL. / PubMed:24550723
MethodsX-ray diffraction
Resolution2.557 Å
Structure data

PDB-4l3e:
The complex between high affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide
Method: X-RAY DIFFRACTION / Resolution: 2.557 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / receptors / membrane

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