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Structure paper

TitleStructural basis for the electron transfer from an open form of NADPH-cytochrome P450 oxidoreductase to heme oxygenase.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 111, Page 2524-2529, Year 2014
Publish dateOct 31, 2013 (structure data deposition date)
AuthorsSugishima, M. / Sato, H. / Higashimoto, Y. / Harada, J. / Wada, K. / Fukuyama, K. / Noguchi, M.
External linksProc. Natl. Acad. Sci. USA / PubMed:24550278
MethodsX-ray diffraction
Resolution4.3 Å
Structure data

PDB-3wkt:
Complex structure of an open form of NADPH-cytochrome P450 reductase and heme oxygenase-1
Method: X-RAY DIFFRACTION / Resolution: 4.3 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

Source
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / Heme degradation / Microsomal membrane

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