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Structure paper

TitleImmunoglobulin g1 fc domain motions: implications for fc engineering.
Journal, issue, pagesJ. Mol. Biol., Vol. 426, Page 1799-1811, Year 2014
Publish dateMay 21, 2013 (structure data deposition date)
AuthorsFrank, M. / Walker, R.C. / Lanzilotta, W.N. / Prestegard, J.H. / Barb, A.W.
External linksJ. Mol. Biol. / PubMed:24522230
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-4ku1:
Role of the hinge and C-gamma-2/C-gamma-3 interface in immunoglobin G1 Fc domain motions: implications for Fc engineering
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / human Fc Fragment / immune response

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