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TitleDiscovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A.
Journal, issue, pagesJ. Med. Chem., Vol. 57, Page 2455-2461, Year 2014
Publish dateOct 22, 2013 (structure data deposition date)
AuthorsFrank, A.O. / Vangamudi, B. / Feldkamp, M.D. / Souza-Fagundes, E.M. / Luzwick, J.W. / Cortez, D. / Olejniczak, E.T. / Waterson, A.G. / Rossanese, O.W. / Chazin, W.J. / Fesik, S.W.
External linksJ. Med. Chem. / PubMed:24491171
MethodsX-ray diffraction
Resolution1.35 Å
Structure data

PDB-4nb3:
Crystal structure of RPA70N in complex with a 3,4 dichlorophenylalanine ATRIP derived peptide
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPEPTIDE BINDING PROTEIN / OB fold / Protein-Protein Interaction / 3 / 4 dichlorophenylalanine

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