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-Structure paper
Title | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. |
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Journal, issue, pages | Cell Rep, Vol. 6, Page 421-430, Year 2014 |
Publish date | Dec 20, 2013 (structure data deposition date) |
Authors | Zhang, X. / Wu, J. / Du, F. / Xu, H. / Sun, L. / Chen, Z. / Brautigam, C.A. / Chen, Z.J. |
External links | Cell Rep / PubMed:24462292 |
Methods | X-ray diffraction |
Resolution | 1.859 - 2.444 Å |
Structure data | PDB-4o67: PDB-4o68: PDB-4o69: PDB-4o6a: |
Chemicals | ChemComp-1SY: ChemComp-ZN: ChemComp-HOH: ChemComp-SO4: |
Source |
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Keywords | TRANSFERASE / immune response / immune responses / TRANSFERASE/DNA / TRANSFERASE-DNA complex |