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TitleTwo potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations.
Journal, issue, pagesNat Commun, Vol. 5, Page 3139-3139, Year 2014
Publish dateJul 9, 2013 (structure data deposition date)
AuthorsChu, H.M. / Wright, J. / Chan, Y.H. / Lin, C.J. / Chang, T.W. / Lim, C.
External linksNat Commun / PubMed:24457896
MethodsX-ray diffraction
Resolution1.92 Å
Structure data

PDB-4lkx:
Humanized antibody 4B12 Fab complexed with a CemX segment
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Immunoglobulin / antibody / Fab-peptide complex

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