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Structure paper

TitleTargeting gamma-herpesvirus 68 Bcl-2-mediated down-regulation of autophagy.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 8029-8040, Year 2014
Publish dateAug 30, 2013 (structure data deposition date)
AuthorsSu, M. / Mei, Y. / Sanishvili, R. / Levine, B. / Colbert, C.L. / Sinha, S.
External linksJ. Biol. Chem. / PubMed:24443581
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-4mi8:
Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and a Beclin 1 BH3 domain-derived peptide
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • murid herpesvirus 4 (Murine herpesvirus 68)
  • homo sapiens (human)
KeywordsVIRAL PROTEIN/APOPTOSIS / BH3D / Bcl-2 family / anti-apoptotic and anti-autophagic activities / VIRAL PROTEIN-APOPTOSIS complex

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