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-Structure paper
Title | Human 3-alpha hydroxysteroid dehydrogenase type 3 (3 alpha-HSD3): The V54L mutation restricting the steroid alternative binding and enhancing the 20 alpha-HSD activity |
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Journal, issue, pages | J. Steroid Biochem. Mol. Biol., Vol. 141, Page 135-143, Year 2014 |
Publish date | Jun 3, 2013 (structure data deposition date) |
Authors | Zhang, B. / Zhu, D.-W. / Hu, X.-J. / Zhou, M. / Shang, P. / Lin, S.-X. |
External links | J. Steroid Biochem. Mol. Biol. / PubMed:24434280 |
Methods | X-ray diffraction |
Resolution | 2 - 2.2 Å |
Structure data | PDB-4l1w: PDB-4l1x: |
Chemicals | ChemComp-NAP: ChemComp-STR: ChemComp-SO4: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / ALPHA-BETA BARREL / HUMAN 3-ALPHA HSD3 / AKR / AKR1C2 / ALDO-KETO REDUCTASE / NADPH |