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Structure paper

TitleMolecular control of delta-opioid receptor signalling.
Journal, issue, pagesNature, Vol. 506, Page 191-196, Year 2014
Publish dateOct 12, 2013 (structure data deposition date)
AuthorsFenalti, G. / Giguere, P.M. / Katritch, V. / Huang, X.P. / Thompson, A.A. / Cherezov, V. / Roth, B.L. / Stevens, R.C.
External linksNature / PubMed:24413399
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-4n6h:
1.8 A Structure of the human delta opioid 7TM receptor (PSI Community Target)
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-OLA:
OLEIC ACID

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-EJ4:
(4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol / antagonist*YM

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / human opioid receptor / sodium regulation / allostery / functional selectivity / GPCR signaling / constitutive activity / GPCR network / membrane protein / PSI-Biology / Structural Genomics / GPCR / membrane

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