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-Structure paper
Title | Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept. |
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Journal, issue, pages | J. Med. Chem., Vol. 57, Page 309-324, Year 2014 |
Publish date | Sep 18, 2013 (structure data deposition date) |
![]() | Ashton, K.S. / Andrews, K.L. / Bryan, M.C. / Chen, J. / Chen, K. / Chen, M. / Chmait, S. / Croghan, M. / Cupples, R. / Fotsch, C. ...Ashton, K.S. / Andrews, K.L. / Bryan, M.C. / Chen, J. / Chen, K. / Chen, M. / Chmait, S. / Croghan, M. / Cupples, R. / Fotsch, C. / Helmering, J. / Jordan, S.R. / Kurzeja, R.J. / Michelsen, K. / Pennington, L.D. / Poon, S.F. / Sivits, G. / Van, G. / Vonderfecht, S.L. / Wahl, R.C. / Zhang, J. / Lloyd, D.J. / Hale, C. / St Jean, D.J. |
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Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | ![]() PDB-4msu: |
Chemicals | ![]() ChemComp-2EU: ![]() ChemComp-S6P: ![]() ChemComp-IOD: ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
Source |
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![]() | SUGAR BINDING PROTEIN / SIS domains / Regulatory protein / glucokinase / phospho-fructose |