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TitleDevelopment of Accessible Peptidic Tool Compounds to Study the Phosphatase Ptp1B in Intact Cells.
Journal, issue, pagesAcs Chem. Biol., Vol. 9, Page 769-, Year 2014
Publish dateFeb 12, 2013 (structure data deposition date)
AuthorsMeyer, C. / Hoeger, B. / Temmerman, K. / Tatarek-Nossol, M. / Pogenberg, V. / Bernhagen, J. / Wilmanns, M. / Kapurniotu, A. / Kohn, M.
External linksAcs Chem. Biol. / PubMed:24387659
MethodsX-ray diffraction
Resolution2.619 - 3.3 Å
Structure data

PDB-3zmp:
Src-derived peptide inhibitor complex of PTP1B
Method: X-RAY DIFFRACTION / Resolution: 2.619 Å

PDB-3zmq:
Src-derived mutant peptide inhibitor complex of PTP1B
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/PEPTIDE / HYDROLASE-PEPTIDE COMPLEX / ENZYME INHIBITORS / STRUCTURE-ACTIVITY RELATIONSHIP / TRANSFERASE

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