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Structure paper

TitleCrystal structure of a novel asymmetrically engineered Fc variant with improved affinity for Fc gamma Rs.
Journal, issue, pagesMol. Immunol., Vol. 58, Page 132-138, Year 2014
Publish dateDec 5, 2013 (structure data deposition date)
AuthorsMimoto, F. / Kadono, S. / Katada, H. / Igawa, T. / Kamikawa, T. / Hattori, K.
External linksMol. Immunol. / PubMed:24334029
MethodsX-ray diffraction
Resolution2.78 Å
Structure data

PDB-3wn5:
Crystal structure of asymmetrically engineered Fc variant in complex with FcgRIIIa
Method: X-RAY DIFFRACTION / Resolution: 2.78 Å

Chemicals

ChemComp-IOD:
IODIDE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / RECEPTOR COMPLEX / FC RECEPTOR / ANTIBODY

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