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Structure paper

TitleA Noncompetitive Inhibitor for Mycobacterium tuberculosis's Class IIa Fructose 1,6-Bisphosphate Aldolase.
Journal, issue, pagesBiochemistry, Vol. 53, Page 202-213, Year 2014
Publish dateJul 25, 2013 (structure data deposition date)
AuthorsCapodagli, G.C. / Sedhom, W.G. / Jackson, M. / Ahrendt, K.A. / Pegan, S.D.
External linksBiochemistry / PubMed:24325645
MethodsX-ray diffraction
Resolution2.08 Å
Structure data

PDB-4lv4:
A noncompetitive inhibitor for M. tuberculosis's class IIa fructose 1,6-bisphosphate aldolase
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-8HC:
8-hydroxyquinoline-2-carboxylic acid

ChemComp-ACT:
ACETATE ION

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsLYASE/LYASE INHIBITOR / CLASS II FRUCTOSE-1 / 6-BISPHOSPHATE ALDOLASE / ZINC ENZYME / MYCOBACTERIUM TUBERCULOSIS / DIHYDROXYACETONE / GLYCERALDEHYDE-3-PHOSPHATE / ALDOL CONDENSATION / GLYCOLYSIS / LYASE / METAL-BINDING / 8-HYDROXYQUINOLINE-2-CARBOXYLIC ACID / LYASE-LYASE INHIBITOR complex

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