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Structure paper

TitleOrphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.
Journal, issue, pagesNat. Chem. Biol., Vol. 10, Page 133-140, Year 2014
Publish dateMar 4, 2013 (structure data deposition date)
AuthorsWang, W. / Wang, Y. / Chen, H. / Xing, Y. / Li, F. / Zhang, Q. / Zhou, B. / Zhang, H. / Zhang, J. / Bian, X. ...Wang, W. / Wang, Y. / Chen, H. / Xing, Y. / Li, F. / Zhang, Q. / Zhou, B. / Zhang, H. / Zhang, J. / Bian, X. / Li, L. / Liu, Y. / Zhao, B. / Chen, Y. / Wu, R. / Li, A. / Yao, L. / Chen, P. / Zhang, Y. / Tian, X. / Beermann, F. / Wu, M. / Han, J. / Huang, P. / Lin, T. / Wu, Q.
External linksNat. Chem. Biol. / PubMed:24316735
MethodsX-ray diffraction
Resolution2.12 - 3.01 Å
Structure data

PDB-4jgv:
Crystal Structure of Human Nur77 Ligand-binding Domain in Complex with THPN
Method: X-RAY DIFFRACTION / Resolution: 3.01 Å

PDB-4kzi:
Crystal Structure of TR3 LBD in complex with DPDO
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

PDB-4kzj:
Crystal Structure of TR3 LBD L449W Mutant
Method: X-RAY DIFFRACTION / Resolution: 2.12 Å

PDB-4kzm:
Crystal Structure of TR3 LBD S553A Mutant
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-T94:
1-(3,4,5-trihydroxyphenyl)nonan-1-one

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ZJ0:
1-(3,5-dimethoxyphenyl)decan-1-one

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / ORPHAN NUCLEAR RECEPTOR

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