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TitleStructural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Journal, issue, pagesCell Rep, Vol. 5, Page 1443-1455, Year 2013
Publish dateNov 5, 2013 (structure data deposition date)
AuthorsWu, Y. / West, A.P. / Kim, H.J. / Thornton, M.E. / Ward, A.B. / Bjorkman, P.J.
External linksCell Rep / PubMed:24316082
MethodsX-ray diffraction
Resolution6.5 - 8.001 Å
Structure data

PDB-4nhg:
Crystal Structure of 2G12 IgG Dimer
Method: X-RAY DIFFRACTION / Resolution: 8.001 Å

PDB-4nhh:
Structure of 2G12 IgG Dimer
Method: X-RAY DIFFRACTION / Resolution: 6.5 Å

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Ig fold / antibody / Ig

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