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Structure paper

TitleA photoswitchable neurotransmitter analogue bound to its receptor.
Journal, issue, pagesBiochemistry, Vol. 52, Page 8972-8974, Year 2013
Publish dateSep 22, 2012 (structure data deposition date)
AuthorsReiter, A. / Skerra, A. / Trauner, D. / Schiefner, A.
External linksBiochemistry / PubMed:24295282
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-4h8i:
Structure of GluK2-LBD in complex with GluAzo
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-11W:
(4R)-4-[(2E)-3-{4-[(E)-phenyldiazenyl]phenyl}prop-2-en-1-yl]-L-glutamic acid

ChemComp-CL:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsSIGNALING PROTEIN / membrane protein / glycoprotein / transmembrane protein / ligand-binding domain / ion transport / ion channel / ionotropic glutamate receptor / kainate receptor / GluAzo / PCL / photochromic ligand / MES / synapse / presynaptic cell membrane / postsynaptic cell membrane

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