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TitleStructure of MurNAc 6-phosphate hydrolase (MurQ) from Haemophilus influenzae with a bound inhibitor.
Journal, issue, pagesBiochemistry, Vol. 52, Page 9358-9366, Year 2013
Publish dateJul 31, 2013 (structure data deposition date)
AuthorsHadi, T. / Hazra, S. / Tanner, M.E. / Blanchard, J.S.
External linksBiochemistry / PubMed:24251551
MethodsX-ray diffraction
Resolution2.405 - 2.577 Å
Structure data

PDB-4lzj:
Crystal Structure of MurQ from H.influenzae with bound inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.405 Å

PDB-4m0d:
Crystal structure of MurQ from H.influenzae in apo form
Method: X-RAY DIFFRACTION / Resolution: 2.577 Å

Chemicals

ChemComp-22H:
2-(acetylamino)-3-O-[(1R)-1-carboxyethyl]-2-deoxy-6-O-phosphono-D-glucitol

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • haemophilus influenzae (bacteria)
KeywordsLYASE/LYASE INHIBITOR / Alpha-Beta-Alpha sandwich / MurQ / YfeU / Protein-Ligand complex / NAD(P)/FAD-binding Rossmann fold / D-muramitol 6-phosphate / LYASE-LYASE INHIBITOR complex / LYASE / NAD(P)/FAD- binding Rossmann fold

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