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TitleA novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication.
Journal, issue, pagesChem. Commun. (Camb. ), Vol. 50, Page 368-370, Year 2014
Publish dateAug 1, 2012 (structure data deposition date)
AuthorsLee, M.K. / Bottini, A. / Kim, M. / Bardaro, M.F. / Zhang, Z. / Pellecchia, M. / Choi, B.S. / Varani, G.
External linksChem. Commun. (Camb. ) / PubMed:24247110
MethodsNMR (solution)
Structure data

PDB-2lwk:
Solution structure of small molecule-influenza RNA complex
Method: SOLUTION NMR

Chemicals

ChemComp-0EC:
6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine

KeywordsRNA / double helix / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease / SSGCID

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