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TitleComplexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Journal, issue, pagesPlos One, Vol. 8, Page e78187-e78187, Year 2013
Publish dateMay 1, 2013 (structure data deposition date)
AuthorsGustchina, E. / Li, M. / Ghirlando, R. / Schuck, P. / Louis, J.M. / Pierson, J. / Rao, P. / Subramaniam, S. / Gustchina, A. / Clore, G.M. / Wlodawer, A.
External linksPlos One / PubMed:24244293
MethodsX-ray diffraction
Resolution2.817 - 2.921 Å
Structure data

PDB-4kht:
Triple helix bundle of GP41 complexed with fab 8066
Method: X-RAY DIFFRACTION / Resolution: 2.817 Å

PDB-4khx:
Crystal structure of gp41 helix complexed with antibody 8062
Method: X-RAY DIFFRACTION / Resolution: 2.921 Å

Source
  • human immunodeficiency virus 1
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / GP41 fab immune system / gp41

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