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Structure paper

TitleThe crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 885-894, Year 2014
Publish dateAug 4, 2013 (structure data deposition date)
AuthorsJacobson, J.M. / Yin, J. / Kitov, P.I. / Mulvey, G. / Griener, T.P. / James, M.N. / Armstrong, G. / Bundle, D.R.
External linksJ. Biol. Chem. / PubMed:24225957
MethodsX-ray diffraction
Resolution1.56 Å
Structure data

PDB-4m1u:
The crystal structure of Stx2 and a disaccharide ligand
Method: X-RAY DIFFRACTION / Resolution: 1.56 Å

Chemicals

ChemComp-1PS:
3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE

ChemComp-HOH:
WATER

Source
  • escherichia coli o157:h7 (bacteria)
  • escherichia coli (E. coli)
KeywordsHYDROLASE / rRNA N-glycosylase

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