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-Structure paper
Title | Discovery and Characterization of a Novel Dihydroisoxazole Class of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Potentiators. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 9180-9191, Year 2013 |
Publish date | Jul 31, 2013 (structure data deposition date) |
![]() | Patel, N.C. / Schwarz, J. / Hou, X.J. / Hoover, D.J. / Xie, L. / Fliri, A.J. / Gallaschun, R.J. / Lazzaro, J.T. / Bryce, D.K. / Hoffmann, W.E. ...Patel, N.C. / Schwarz, J. / Hou, X.J. / Hoover, D.J. / Xie, L. / Fliri, A.J. / Gallaschun, R.J. / Lazzaro, J.T. / Bryce, D.K. / Hoffmann, W.E. / Hanks, A.N. / McGinnis, D. / Marr, E.S. / Gazard, J.L. / Hajos, M. / Scialis, R.J. / Hurst, R.S. / Shaffer, C.L. / Pandit, J. / O'Donnell, C.J. |
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Methods | X-ray diffraction |
Resolution | 1.5 - 2.1 Å |
Structure data | ![]() PDB-4lz5: ![]() PDB-4lz7: ![]() PDB-4lz8: |
Chemicals | ![]() ChemComp-GLU: ![]() ChemComp-ZN: ![]() ChemComp-1YV: ![]() ChemComp-HOH: ![]() ChemComp-1YW: ![]() ChemComp-1YX: |
Source |
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![]() | TRANSPORT PROTEIN / AMPA receptor / allosteric modulator |