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-Structure paper
Title | Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor. |
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Journal, issue, pages | J. Biol. Chem., Vol. 288, Page 36168-36178, Year 2013 |
Publish date | Jun 26, 2013 (structure data deposition date) |
Authors | Mukund, S. / Shang, Y. / Clarke, H.J. / Madjidi, A. / Corn, J.E. / Kates, L. / Kolumam, G. / Chiang, V. / Luis, E. / Murray, J. ...Mukund, S. / Shang, Y. / Clarke, H.J. / Madjidi, A. / Corn, J.E. / Kates, L. / Kolumam, G. / Chiang, V. / Luis, E. / Murray, J. / Zhang, Y. / Hotzel, I. / Koth, C.M. / Allan, B.B. |
External links | J. Biol. Chem. / PubMed:24189067 |
Methods | X-ray diffraction |
Resolution | 2.02 - 2.735 Å |
Structure data | PDB-4lex: PDB-4lf3: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / Fab fragment / anti-GCGR / Fab heavy and light chain / Antibody / GCGR |