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Structure paper

TitleDynamic elements govern the catalytic activity of CapE, a capsular polysaccharide-synthesizing enzyme from Staphylococcus aureus.
Journal, issue, pagesFebs Lett., Vol. 587, Page 3824-3830, Year 2013
Publish dateJul 18, 2012 (structure data deposition date)
AuthorsMiyafusa, T. / Caaveiro, J.M. / Tanaka, Y. / Tsumoto, K.
External linksFebs Lett. / PubMed:24157361
MethodsX-ray diffraction
Resolution1.88 Å
Structure data

PDB-4g5h:
Crystal structure of capsular polysaccharide synthesizing enzyme CapE from Staphylococcus aureus in complex with by-product
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-UD7:
[(2R,3R,4R,6R)-3-acetamido-6-methyl-4-oxidanyl-5-oxidanylidene-oxan-2-yl] [[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate

ChemComp-FMT:
FORMIC ACID

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus (bacteria)
KeywordsLYASE / Rossmann fold / Short-chain dehydrogenase/reductase / capsular polysaccharide synthesis / oxidase / epimerase

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