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TitleMolecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region
Journal, issue, pagesPlos One, Vol. 8, Page 77266-, Year 2013
Publish dateOct 10, 2012 (structure data deposition date)
AuthorsBourne, Y. / Renault, L. / Essono, S. / Mondielli, G. / Lamourette, P. / Boquet, D. / Grassi, J. / Marchot, P.
External linksPlos One / PubMed:24146971
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-2ymx:
Crystal structure of inhibitory anti-AChE Fab408
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / ACETYLCHOLINESTERASE / INHIBITION / BACK DOOR REGION

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