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Structure paper

TitleDissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica.
Journal, issue, pagesBiochim. Biophys. Acta, Vol. 1840, Page 464-475, Year 2014
Publish dateMay 15, 2013 (structure data deposition date)
AuthorsChan, C.H. / Newmister, S.A. / Talyor, K. / Claas, K.R. / Rayment, I. / Escalante-Semerena, J.C.
External linksBiochim. Biophys. Acta / PubMed:24121107
MethodsX-ray diffraction
Resolution1.4 - 1.95 Å
Structure data

PDB-4kqf:
Crystal structure of CobT E174A complexed with adenine
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4kqg:
Crystal structure of CobT E174A complexed with DMB
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4kqh:
Crystal structure of CobT E317A
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4kqi:
Crystal structure of CobT E317A complexed with its reaction products
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-4kqj:
Crystal structure of CobT S80Y/Q88M/L175M complexed with p-cresol and NaMN
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-4kqk:
Crystal structure of CobT S80Y/Q88M/L175M complexed with p-cresol
Method: X-RAY DIFFRACTION / Resolution: 1.47 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ADE:
ADENINE

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-DMD:
5,6-DIMETHYLBENZIMIDAZOLE

ChemComp-RBZ:
ALPHA-RIBAZOLE-5'-PHOSPHATE

ChemComp-NIO:
NICOTINIC ACID / medication*YM

ChemComp-NCN:
NICOTINATE MONONUCLEOTIDE

ChemComp-PCR:
P-CRESOL

ChemComp-GOL:
GLYCEROL

Source
  • salmonella enterica subsp. enterica serovar typhimurium (bacteria)
KeywordsTRANSFERASE

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