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Structure paper

TitleStructural and Functional Analysis of Human SIRT1.
Journal, issue, pagesJ. Mol. Biol., Vol. 426, Page 526-541, Year 2014
Publish dateDec 16, 2012 (structure data deposition date)
AuthorsDavenport, A.M. / Huber, F.M. / Hoelz, A.
External linksJ. Mol. Biol. / PubMed:24120939
MethodsX-ray diffraction
Resolution1.849 - 2.64 Å
Structure data

PDB-4ig9:
Structure of NAD-dependent protein deacetylase sirtuin-1 (open state, 2.64 A)
Method: X-RAY DIFFRACTION / Resolution: 2.64 Å

PDB-4kxq:
Structure of NAD-dependent protein deacetylase sirtuin-1 (closed state, 1.85 A)
Method: X-RAY DIFFRACTION / Resolution: 1.849 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-APR:
ADENOSINE-5-DIPHOSPHORIBOSE

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsHYDROLASE / deacetylase

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