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TitleCrystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface.
Journal, issue, pagesStructure, Vol. 21, Page 1966-1978, Year 2013
Publish dateApr 16, 2013 (structure data deposition date)
AuthorsSchmidt, M.M. / Townson, S.A. / Andreucci, A.J. / King, B.M. / Schirmer, E.B. / Murillo, A.J. / Dombrowski, C. / Tisdale, A.W. / Lowden, P.A. / Masci, A.L. ...Schmidt, M.M. / Townson, S.A. / Andreucci, A.J. / King, B.M. / Schirmer, E.B. / Murillo, A.J. / Dombrowski, C. / Tisdale, A.W. / Lowden, P.A. / Masci, A.L. / Kovalchin, J.T. / Erbe, D.V. / Wittrup, K.D. / Furfine, E.S. / Barnes, T.M.
External linksStructure / PubMed:24120761
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-4k71:
Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIPID TRANSPORT / MHC Class I / Endosome Recycling / Endosome

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