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TitleThe Hydrogen Peroxide Induced Radical Behaviour in Human Cytochrome C Phospholipid Complexes: Implications for the Enhanced Pro-Apoptotic Activity of the G41S Mutant
Journal, issue, pagesBiochem. J., Vol. 456, Page 441-, Year 2013
Publish dateNov 20, 2012 (structure data deposition date)
AuthorsRajagopal, B.S. / Edzuma, A.N. / Hough, M.A. / Blundell, K.L.I.M. / Kagan, V.E. / Kapralov, A.A. / Fraser, L.A. / Butt, J.N. / Silkstone, G.G. / Wilson, M.T. ...Rajagopal, B.S. / Edzuma, A.N. / Hough, M.A. / Blundell, K.L.I.M. / Kagan, V.E. / Kapralov, A.A. / Fraser, L.A. / Butt, J.N. / Silkstone, G.G. / Wilson, M.T. / Svistunenko, D.A. / Worrall, J.A.R.
External linksBiochem. J. / PubMed:24099549
MethodsX-ray diffraction
Resolution1.35 - 1.65 Å
Structure data

PDB-3zcf:
Structure of recombinant human cytochrome c
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-3zoo:
Structure of the Y46F mutant of human cytochrome c
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

Chemicals

ChemComp-HEC:
HEME C

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

Source
  • homo sapiens (human)
KeywordsELECTRON TRANSPORT / RESPIRATION / APOPTOSIS / ELECTRON TRANSFER / OXIDOREDUCTASE

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