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TitleAutoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10.
Journal, issue, pagesPlos Pathog., Vol. 9, Page e1003639-e1003639, Year 2013
Publish dateJul 9, 2013 (structure data deposition date)
AuthorsFinton, K.A. / Larimore, K. / Larman, H.B. / Friend, D. / Correnti, C. / Rupert, P.B. / Elledge, S.J. / Greenberg, P.D. / Strong, R.K.
External linksPlos Pathog. / PubMed:24086134
MethodsX-ray diffraction
Resolution2.39 Å
Structure data

PDB-4llv:
The structure of the unbound form of anti-HIV antibody 4E10 Fv
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / 4E10 / FV / HIV / immunoglobulin / Antibody

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