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TitleDefining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 16778-16783, Year 2013
Publish dateNov 28, 2012 (structure data deposition date)
AuthorsIslam, K. / Chen, Y. / Wu, H. / Bothwell, I.R. / Blum, G.J. / Zeng, H. / Dong, A. / Zheng, W. / Min, J. / Deng, H. / Luo, M.
External linksProc. Natl. Acad. Sci. USA / PubMed:24082136
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-4i51:
Methyltransferase domain of HUMAN EUCHROMATIC HISTONE METHYLTRANSFERASE 1, mutant Y1211A
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTransferase/Peptide / NE-ALLYL PEPTIDE / STRUCTURAL GENOMICS CONSORTIUM / Transferase-Peptide complex / SGC

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