+Search query
-Structure paper
Title | Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors |
---|---|
Journal, issue, pages | Bioorg. Med. Chem., Vol. 21, Page 6349-6358, Year 2013 |
Publish date | Apr 3, 2013 (structure data deposition date) |
![]() | Deng, G. / Zhao, B. / Ma, Y. / Xu, Q. / Wang, H. / Yang, L. / Zhang, Q. / Guo, T.B. / Zhang, W. / Jiao, Y. ...Deng, G. / Zhao, B. / Ma, Y. / Xu, Q. / Wang, H. / Yang, L. / Zhang, Q. / Guo, T.B. / Zhang, W. / Jiao, Y. / Cai, X. / Zhang, J. / Liu, H. / Guan, X. / Lu, H. / Xiang, J. / Elliott, J.D. / Lin, X. / Ren, F. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | ![]() PDB-4jzr: |
Chemicals | ![]() ChemComp-NI: ![]() ChemComp-4JR: ![]() ChemComp-EDO: ![]() ChemComp-HOH: |
Source |
|
![]() | OXIDOREDUCTASE / Prolyl hydroxylase |