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-Structure paper
| Title | Linking phenotype to kinase: identification of a novel benzoxaborole hinge-binding motif for kinase inhibition and development of high-potency rho kinase inhibitors. |
|---|---|
| Journal, issue, pages | J. Pharmacol. Exp. Ther., Vol. 347, Page 615-625, Year 2013 |
| Publish date | Jun 12, 2013 (structure data deposition date) |
Authors | Akama, T. / Dong, C. / Virtucio, C. / Sullivan, D. / Zhou, Y. / Zhang, Y.K. / Rock, F. / Freund, Y. / Liu, L. / Bu, W. ...Akama, T. / Dong, C. / Virtucio, C. / Sullivan, D. / Zhou, Y. / Zhang, Y.K. / Rock, F. / Freund, Y. / Liu, L. / Bu, W. / Wu, A. / Fan, X.Q. / Jarnagin, K. |
External links | J. Pharmacol. Exp. Ther. / PubMed:24049062 |
| Methods | X-ray diffraction |
| Resolution | 2.79 Å |
| Structure data | ![]() PDB-4l6q: |
| Chemicals | ![]() ChemComp-1WU: ![]() ChemComp-HOH: |
| Source |
|
Keywords | Transferase/Transferase Inhibitor / Transferase-Transferase Inhibitor complex |
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homo sapiens (human)
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