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Structure paper

TitleMolecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 15973-15978, Year 2013
Publish dateApr 29, 2013 (structure data deposition date)
AuthorsGarland, A.L. / Walton, W.G. / Coakley, R.D. / Tan, C.D. / Gilmore, R.C. / Hobbs, C.A. / Tripathy, A. / Clunes, L.A. / Bencharit, S. / Stutts, M.J. ...Garland, A.L. / Walton, W.G. / Coakley, R.D. / Tan, C.D. / Gilmore, R.C. / Hobbs, C.A. / Tripathy, A. / Clunes, L.A. / Bencharit, S. / Stutts, M.J. / Betts, L. / Redinbo, M.R. / Tarran, R.
External linksProc. Natl. Acad. Sci. USA / PubMed:24043776
MethodsX-ray diffraction
Resolution2.806 - 3.194 Å
Structure data

PDB-4kgh:
Crystal Structure of human splunc1 lacking the secretion signal sequence
Method: X-RAY DIFFRACTION / Resolution: 2.806 Å

PDB-4kgo:
Crystal Structure of double Leucine to Methionine mutant human splunc1 lacking the secretion signal sequence
Method: X-RAY DIFFRACTION / Resolution: 3.194 Å

Chemicals

ChemComp-NO3:
NITRATE ION

ChemComp-NH4:
AMMONIUM ION

ChemComp-NA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / beta barrel; BPI-like fold

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