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Structure paper

TitleThe crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid.
Journal, issue, pagesProteins, Vol. 82, Page 405-414, Year 2014
Publish dateMay 24, 2013 (structure data deposition date)
AuthorsMalik, S.S. / Patterson, D.N. / Ncube, Z. / Toth, E.A.
External linksProteins / PubMed:24038671
MethodsX-ray diffraction
Resolution2.55 - 2.797 Å
Structure data

PDB-4kwv:
Crystal Structure of human apo-QPRT
Method: X-RAY DIFFRACTION / Resolution: 2.797 Å

PDB-4kww:
The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PHT:
PHTHALIC ACID

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / NAD / metabolism / type II phosphoribosyltransferase / quinolinic acid / PRPP / brain / TRANSFERASE/TRANSFERASE INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR complex

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