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Structure paper

TitleFluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Journal, issue, pagesNat. Chem. Biol., Vol. 9, Page 721-725, Year 2013
Publish dateMay 3, 2013 (structure data deposition date)
AuthorsLim, H.H. / Stockbridge, R.B. / Miller, C.
External linksNat. Chem. Biol. / PubMed:24036509
MethodsX-ray diffraction
Resolution2.85 - 3.2 Å
Structure data

PDB-4kjp:
Structure of the CLC-ec1 deltaNC construct in the absence of halide
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-4kjq:
Structure of the CLC-ec1 deltaNC construct in 100mM fluoride
Method: X-RAY DIFFRACTION / Resolution: 2.875 Å

PDB-4kjw:
Structure of the CLC-ec1 deltaNC construct in 100mM fluoride and 20mM bromide
Method: X-RAY DIFFRACTION / Resolution: 3.03 Å

PDB-4kk5:
Structure of the CLC-ec1 deltaNC construct in 20mM fluoride and 20mM bromide
Method: X-RAY DIFFRACTION / Resolution: 3.171 Å

PDB-4kk6:
Structure of CLC-ec1 deltaNC construct in 20mM Bromide
Method: X-RAY DIFFRACTION / Resolution: 3.183 Å

PDB-4kk8:
Structure of the E148Q mutant of CLC-ec1 deltaNC construct in 100mM fluoride
Method: X-RAY DIFFRACTION / Resolution: 2.86 Å

PDB-4kk9:
Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 2mM Bromide
Method: X-RAY DIFFRACTION / Resolution: 2.997 Å

PDB-4kka:
Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 20mM Bromide
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-4kkb:
Structure of the E148A mutant of CLC-ec1 deltaNC construct in 20mM fluoride and 20mM Bromide
Method: X-RAY DIFFRACTION / Resolution: 3.021 Å

PDB-4kkc:
Structure of the E148A mutant of CLC-ec1 deltaNC construct in 20mM Bromide
Method: X-RAY DIFFRACTION / Resolution: 3.18 Å

PDB-4kkl:
Structure of the E148A mutant of CLC-ec1 delta NC construct in 100mM fluoride
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

Chemicals

ChemComp-F:
FLUORIDE ION

ChemComp-BR:
BROMIDE ION

Source
  • escherichia coli (E. coli)
  • mus musculus (house mouse)
Keywordstranport protein / membrane protein / membrane transporting protein / membrane transporter / fluoride / TRANSPORT PROTEIN / bromide

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