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TitleA Crystal Structure of the Dengue Virus Ns5 Polymerase Delineates Inter-Domain Amino Acids Residues that Enhance its Thermostability and De Novo Initiation Activities.
Journal, issue, pagesJ. Biol. Chem., Vol. 288, Page 31105-, Year 2013
Publish dateAug 9, 2013 (structure data deposition date)
AuthorsLim, S.P. / Koh, J.H.K. / Seh, C.C. / Liew, C.W. / Davidson, A.D. / Chua, L.S. / Chandrasekaran, R. / Cornvik, T.C. / Shi, P. / Lescar, J.
External linksJ. Biol. Chem. / PubMed:24025331
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-4c11:
Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • dengue virus
KeywordsTRANSFERASE / RNA DEPENDENT RNA POLYMERASE

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